HMMScore is our new platform for the identification of peptides by tandem mass spectrometry (MS/MS). It has very high accuracy because it takes into account several spectral characteristics learned from large data sets, including:
- The mass distribution of peaks
- The intensity distribution of peaks
- The likelihood of fragmentation given the adjacent amino acids.

The statistics are based on our paper in Analytical Chemistry, and the article describing the HMM itself was just published for advance access in Bioinformatics.

The standalone software is available via our Downloads page, and it has also been incorporated into our latest release of GFS, version 2.1, which will be posted to our website in late January 2008.

We will post further updates to the program here, we are working on a number of new features.




HMM_Score HMM